Induced Foxp3+ T-regulatory cells (iTreg) are crucial to gastrointestinal immune system homeostasis and lack of the capability to develop iTregs can lead to autoimmune colitis. we utilized pharmacologic Sirt1 targeting of mice getting multiple cycles of dextran sodium sulfate (DSS) within their normal water alternated with refreshing water. Also wild-type mice getting cyclic DSS and… Continue reading Induced Foxp3+ T-regulatory cells (iTreg) are crucial to gastrointestinal immune system