Bone morphogenetic proteins (BMPs) regulate diverse cellular reactions during embryogenesis and in adulthood including cell differentiation, proliferation, and death in various cells. thrombospondin-1 (TSP-1). Surface plasmon resonance and co-immunoprecipitation confirmed that recombinant human being TSP-1 can bind BMP-2 and -4 and antagonize their effects on C3H10T1/2 cells. Moreover, TSP-1 inhibited the action of serum BMPs.… Continue reading Bone morphogenetic proteins (BMPs) regulate diverse cellular reactions during embryogenesis and