Chlorpromazine (CPZ), a potent nicotinic acetylcholine receptor (nAChR) non-competitive antagonist, binds with higher affinity in the ion route in the desensitized condition than in the closed route condition and with low affinity to additional sites in nAChR-rich membranes. the ion route. [3H]CPZ photolabeling isn’t discovered in the transmembrane domains beyond your ion route, nonetheless it… Continue reading Chlorpromazine (CPZ), a potent nicotinic acetylcholine receptor (nAChR) non-competitive antagonist, binds